Pharmacovigilance (PV) Literature Monitoring with Dialog Solutions
Pharmaceutical companies of all sizes, contract research organisations, medical device manufacturers, biotech and biopharma firms use our drug safety literature screening solution to identify and review articles for Individual Case Safety Reporting, Aggregate Reporting (including PBRER, PSUR and DSUR) and Safety Signals detection.
Our modular, end-to-end approach to drug safety reporting means we can improve every element of this process:
Comprehensive scientific and medical literature
We provide access to all essential content databases for pharmacovigilance through the Dialog® platform.
Databases available through Dialog include Embase, MEDLINE, International Pharmaceutical Abstracts, Allied and Complementary Medicine and BIOSIS.
Dialog®
The Dialog platform delivers a consistent search experience across multiple databases, ensuring all relevant drug safety results are identified. With precision search, deduplication and quality XML output, Dialog is the industry standard for searching medical literature.
Our Literature Search Services team can also create custom, regulatory compliant drug safety search strategies for your medical literature monitoring workflow.
Dialog® Alerts Manager
The Dialog Alerts Manager simplifies the process of automating and managing multiple drug safety searches in Dialog. It also provides a range of features to meet the expectations of regulators and inspectors, such as audit trail of search strategy set up and changes and alert delivery history.
Dialog®ML
DialogML is part of Dialog and uses artificial intelligence to make the literature review process quicker, more efficient and more thorough.
DialogML enhances Dialog alerts by identifying references in scientific literature that meet the criteria for ICSR, Aggregate Reports or Safety Signals and applying a patient safety relevancy ranking to each reference and specific drug safety tags. This means the most relevant and important references are presented to reviewers at the front of the queue helping them better prioritise their workload, find relevant articles more quickly, and speed up analysis and review.
Drug Safety TriagerTM
Literature articles retrieved by the Dialog Alerts Manager are integrated directly into Drug Safety TriagerTM, our next-generation GxP validated and audit-ready pharmacovigilance literature monitoring solution. It makes the drug safety literature monitoring process more efficient, cost-effective and compliant. The system streamlines the literature monitoring workflow by eliminating duplicated content, reducing the volume of literature to be reviewed and automatically outputting literature references relevant for patient safety issues.
In addition, Drug Safety Triager adds artificial intelligence assistance to the literature review process without introducing additional risk. It also gathers evidence for continuous algorithm improvement, paving the way for future phases of automated submission of the most relevant articles and elimination of the most irrelevant articles.
Literature Screening ServicesTM
Our literature monitoring team helps our customers with critical, time-consuming and resource-intensive tasks within the drug safety monitoring workflow.
